Inflammation Learning Module

Presented below is a small module that can be used for instruction on Inflammation and Repair.


Teaching Module: Inflammation and Repair

Ibsen.Phelan Oral Pathology for the Dental Hygienist 5th edition

Grade Level: Post Secondary

Standards:  CODA

Technology Integration: Power Point, Internet, Socrative, Study Blue Flashcards, You Tube video, Blog, Mixbooks, E-journal,  Blooms Digital Taxonomy

Chapter Objectives: (Bloom’s in Italics)

After studying the chapter the student will be able to:


  1. Identify the five classic signs of inflammation that occur locally at the site of inflammation
  2. Identify and categorize three major signs of systemic inflammation
  3. Identify and describe the microscopic events that occur during inflammation
  4. Identify and describe the involvement of white blood cells in the inflammatory process
  5. Identify and describe the systemic manifestations of inflammation
  6. Describe the chronic inflammatory process
  7. Describe and discuss the regeneration and repair process
  8. Discuss and describe conditions associated with injuries to dentition
  9. Discuss and describe the injuries to oral soft tissues from inflammation
  10. Discuss and describe oral conditions associated with connective tissue hyperplasia

Teaching Focus:

Inflammation, immunity and repair are the body’s responses to injury. Inflammation allows the human body to eliminate injurious agents, contain injuries and begin the process of healing. The focus of the topic is to instruct the students on inflammation and repair and create an understanding of each process that can then be related intraorally. Several conditions are the focus of inflammation and repair and the signs and symptoms of each condition should be addressed, along with diagnosis, and treatment of each condition presented.  Case studies should be integrated for critical thinking and problem based learning skills.

Chapter Assessments:

Socrative, Quiz, Review Chapter questions, Case study (blog) and below

Case Study Review:

The case study is to be reviewed in conjunction with PowerPoint presentation, after which the students will discuss their rational for diagnosis.  A submission of an e- journal with personal diagnosis and rational with treatment plan should also be included.

Clinically the interdental papilla was enlarged and had a papillary surface that bled easily when probed. The sessile lesion measured 5 mm cervicoincisally by 3mm mesiodistally. No pain was felt in the area. Information pertinent to the history of the lesion was secured from the mother. The lesion had been there for about 1 year and was first noticed around the time the child began wearing braces. At times tags of the lesion or pieces of it fell off during brushing. The orthodontist pulled most of it off at one point, but it was never surgically removed or submitted for microscopic examination and seemed to grow back. Additional questioning revealed that the child had a wart on her foot within the last year. A biopsy was performed and the tissue sample was placed in formalin and sent to an oral pathology laboratory with the following differential diagnosis

▫         Pyogenic granuloma: the spongy inflammatory tissue was possible caused by the mechanical irritation from the orthodontic bands, thereby causing the pyogenic granuloma.

▫         Papilloma: on the basis of the papillary surface texture of the lesion, it was thought to be a papilloma

▫         Verruca Vulgaris: because the child had a wart and could have spread the virus, Verruca Vulgaris was suggested, in addition this could explain why pieces of the lesion could have fallen off periodically during brushing, however, the surface of a Verruca Vulgaris is usually keratinized and therefore whiter than the lesion illustrated.

The definitive or final diagnosis was pyogenic granuloma

 Case study and picture courtesy of Dr Victor M Sternburg

Diagnosis will be discussed and assessed using Socrative

Case study assessment questions:

  1. What cells appear first during an inflammatory response?
  2. What is the definition of reactive tissue hyperplasia and what forms may be observed within the oral cavity?
  3. What is the clinical diagnosis and rational for this lesion?



3 hours of   presentation

Lecture Outline


Slide   3-4 InflammationTALKING   POINTS:Discuss what inflammation isWhat are the differences between acute   and chronic inflammation?


Slide5-7 Clinical   Signs of InflammationRednessSwellingPainLoss of normal tissue functionTALKING   POINTS:Discuss each sign individually and   describe each eventPictures associated with each sign should    be used and are included in PowerPoint


Slide   8-11 Systemic   Signs of InflammationFeverLeukocytosisElevated C-Reactive ProteinLymphadenopathyTALKING   POINTS:Each sign is described and an event is   associated with each symptomHow does each sign relate to the oral   or periodontal process?

Pictures   depicting each sign   for visual aid

Lecture   Outline


Slide   12-22 Microscopic   events during inflammationInjury to tissueConstriction of the microcirculationDilation of the microcirculationIncrease in permeability of the   microcirculationExudate leaving the microcirculationIncrease in blood viscosity in the   microcirculationDecrease in blood flow through the   microcirculationMargination and pavementing of the   white blood cells

Emigration of white blood cells from   the microcirculation




Discuss each event ( view video   accessed from You Tube)

Discuss incision and drainage   associated with exudate

What are some of the conditions that   could form exudate and how are they treated intraorally?


Slide   23-31 White   Blood Cells and their involvement in the inflammatory responseNeutrophilsMacrophagesHistological slidesTALKING   POINTS:What condition or process involves   Neutrophils and macrophages that also can be associated intraorally?Discuss periodontal disease and the   immune response


Slide   32-38 Biochemical   Mediators of InflammationKinnin SystemClotting MechanismComplement SystemOther biochemical mediatorsInflammatory drugsTALKING   POINTS:Discuss each mediator and how it   factors in with inflammation

Show video of the Kinnin System

Discuss antiinflammatory drugs, what   types are there? What do they do? How do they work?


Slide   39-40 Case   Study (1)See   Case study review above: Use Socrative for your student responseTalking   Points:1.   What cells appear first during an inflammatory response?

  1. What   is the definition of reactive tissue hyperplasia and what forms may be   observed within the oral cavity?
  2. What   is the clinical diagnosis and rational for this lesion?



Slide   41-45 Chronic   InflammationGranulomaHyperplasiaHypertrophyAtrophyTalking Points

  1. Discuss the   clinical manifestations of chronic inflammation as it occurs intraorally.
  2. Are there any   medications associated with hyperplasia, if so how is it treated?


Slide   46- Regeneration   and RepairTalking Points

  1. Discuss what   happens during regeneration vs. what occurs during repair.
  2. Compare and   Contrast the similarities during repair and regeneration


Slide   47-52 Microscopic   Events During RepairDay   of InjuryOne   day after injuryTwo   Days after injurySeven   days after injuryTwo   weeks after InjuryTalking pointsDiscuss   the healing process and the formation of granulation tissue.Give   examples of a surgical incision

What   is a keloid and how does it form?


Slides   52-58 Injuries   to TeethAttritionBruxismAbrasionAbfractionErosionMethamphetamine   UseTalking pointsDiscuss   every injury and supply examples with pictures.

How   does attrition differ from bruxism?

What   is the difference between bulimia and anorexia nervosa? What are treatments   to these conditions?


Slide   59-63 Injuries   to Oral Soft TissuesAspirin   BurnPhenol   BurnElectric   BurnOther   BurnsTalking PointsDiscuss   situations and examples of these various conditionsHow   can we as dental professionals educate our patients concerning these conditions?


Slides   64-75 Lesions   from Self Induced InjuriesHematomaTraumatic   UlcerFrictional   keratosisLinea   AlbaNicotine   StomatitisTobacco   Pouch KeratosisTraumatic   Neuroma Amalgam TattooMelanosis

Solar   Cheilitis



Talking Points

Describe   and give examples and pictures of each condition

Which   condition can lead to serious consequences if any? And Why?


Slide   76-83 Reactive   Connective Tissue HyperplasiaPyogenic   granulomaPeripheral   Giant Cell GranulomaIrritation   fibromaDenture-Induced   Fibrous HyperplasiaPapillary   Hyperplasia of the PalateGingival   EnlargementChronic   Hyperplastic PulpitisTalking Points

Discuss   proliferation of granulation tissue and its treatment



Slide   84-89 Inflammatory   Periapical LesionsPeriapical   abscessDental   or periapical granulomaRadicular   CystResorption   of TeethFocal   Sclerosing OsteomyelitisTalking PointsRadiographic   diagnosis is essential for treatment and a good prognosis of this type of   inflammation. Discuss the outcomes. 


Slide   90 Review   QuestionsWhat   injuries to oral soft tissues may be observed within the oral cavity?What   is the definition of reactive tissue hyperplasia and what forms may be   observed within the oral cavity?What   inflammatory periapical lesions may be observed within the oral cavity?



Assessment Activities:

Mixbooks should be used in conjunction with the case studies. The students will create a photo album of each case study along with other similar conditions associated in this chapter. They will formulate a diagnosis and discuss and collaborate their diagnosis with others in their class. This collaboration should be discussed in the next class for follow up and understanding.

Learning   Assessment Activity   one Activity   Two Activity   Three
Homework   Assignment Socrative   Questions

1.Name one   specific concept you learned today

2. Name a concept   that you did not understand

Case   Study (#2)

Blog Assignment Case study

www.jlutterblogspot.comCase study # 10 

Read   Chapter 2 Ibsen 5th edition Inflammation   and Repair

Quiz10 question quiz   test bank : Taken from Ibsen 5th edition textbook
E-  journal ( e college), Mixbooks



This entry was posted on Saturday, October 20th, 2012 at 3:55 pm and is filed under Instructional Design. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.


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